Percent of persons using at least one prescription drug in the past 30 days: 48.6% (2015-2018) Percent of persons using three or more prescription drugs in the past 30 days: 24% (2015-2018) Percent of persons using five or more prescription drugs in the past 30 days: 12.8% (2015-2018) Source: Health, United States, 2019, table 39. pdf icon..