CF, CRMS and CFTR-related Disorder Diagnoses,2015. CRMS 8.8% CFTR-related Disorder Cystic Fibrosis 5.0% 86.2%. Annual Data Report 2015 Cystic Fibrosis Foundation Patient Registry 13. The majority of those diagnosed in their first year are asymptomatic or minimally symptomatic at time of diagnosis..