COVaxON Report: FREQUENTLY ASKED QUESTIONS - Health …
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What is COVAX?
COVAX is the vaccines pillar of the Access to COVID-19 Tools (ACT) Accelerator
The ACT Accelerator is a ground-breaking global collaboration to accelerate the development, production, and equitable access to COVID-19 tests, treatments, and vaccines.
Where can I find a COVID-19 vaccine booster shot?
Find a COVID-19 vaccine or booster: Search vaccines.gov, text your ZIP code to 438829, or call 1-800-232-0233 to find locations near you.
What happens if I skip the second COVID-19 vaccine shot?
If you've already had COVID-19, you might actually react more strongly to the first dose because your body has already seen the spike protein from your previous infection. In this case, your first dose is acting like your second dose. That said, it's still recommended that you get the second shot.
Do I qualify for an exception or can I apply for an exception to the COVID-19 vaccine requirement?
See full answer
Categories of noncitizen, nonimmigrants that meet the criteria for an exception under the proclamation and CDC’s order include: Persons on diplomatic or official foreign government travel Children under 18 years of age Persons with documented medical contraindications to receiving a COVID-19 vaccine Participants in certain COVID-19 vaccine trials Persons issued a humanitarian or emergency exception Persons with valid visas [excluding B-1 (business) or B-2 (tourism) visas] who are citizens of a foreign country with limited COVID-19 vaccine availability. Members of the U.S. Armed Forces or their spouses or children (under 18 years of age). Sea crew members traveling pursuant to a C-1 and D nonimmigrant visa Persons whose entry would be in the national interest, as determined by the Secretary of State, Secretary of Transportation, or Secretary of Homeland Security (or their designees)
Does Walgreens have Pfizer COVID-19 booster shots?
Walgreens Announces Pfizer COVID-19 Vaccine Booster Shots Now Available Nationwide for Eligible Individuals.
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When should you take the COVID-19 booster vaccine?
The Advisory Committee on Immunization Practices recommends that all persons aged ≥12 years receive a booster dose of COVID-19 vaccine ≥5 months after the second dose of the mRNA vaccine primary series (9).
Is the second COVID-19 shot really necessary?
Key takeaways: It's important to get both doses of the Pfizer and Moderna vaccines to get the most benefit from the two-dose series. Some people may react more strongly to the second shot, but the side effects are temporary and will typically go away within a few days.
Can you wait longer than three weeks between your first and second COVID-19 vaccine?
It may be helpful for some people to wait up to 8 weeks between the first and second doses of the Pfizer/BioNTech and Moderna COVID vaccines, the CDC says in updated guidance.
Should the COVID-19 booster be the same vaccine as the first two shots?
The FDA has authorized three vaccine boosters — Pfizer-BioNTech, Moderna and Janssen/Johnson & Johnson — and determined that it is safe to get a COVID-19 vaccine booster or additional dose that is a different brand than your initial dose or doses.
What are the contraindications to the COVID-19 vaccine?
Contraindications to COVID-19 vaccination include: Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a component of the COVID-19 vaccine. Known diagnosed allergy to a component of the COVID-19 vaccine (see Appendix C for a list of vaccine components).
Does having an autoimmune disease make me more susceptible to COVID-19?
However, depending on the autoimmune disorder and the immunosuppressive medication you are taking, you may be more likely to get seriously ill from COVID-19.Feb 17, 2022
Where can I apply for the humanitarian or emergency exception to travel to the United States?
Individuals who fit the exception criteria described in the Presidential Proclamation and CDCs Amended Order may contact the U.S. embassy or consulate in or nearest the country from which they are departing for the United States. The embassy will then transmit the information to the CDC for consideration.
The Goals of Covax
- In its inception, COVAX planned to deliver 2 billion doses of COVID-19 vaccine by the end of 2021, particularly in low-to-middle income countries. This represents roughly 20% of the vaccine needs of participating countries. Over 90 low-income and middle-income countries will be eligible to receive 1 billion doses of the COVID-19 vaccine at low (estimated at 1.60 USD) or no cost throug…
Covax Achievements to Date
- By the end of August, 330 million doses had been released for delivery, with 230 million being delivered to 142 of the participating economies. According to Gavi the Vaccine Alliance, the key COVAX milestone of two billion doses released for delivery is now expected to be reached in the first quarter of 2022. A further 1.1 billion doses are expected to become available for delivery be…
Covax Supply Forecast: September 2021
- Of these 1.4 billion doses, approximately 1.2 billion will be available for AMC participants. Best amounts to 20% of the population cover, or 40% of the adult population in all 92 countries part of the AMC except India. The supply of COVAX is expected to continue to expand into the first quarter of 2022, reaching it also of 2.6 billion doses availa...
References
- UNICEF. Global leaders commit further support for global equitable access to COVID-19 vaccines and COVAX A joint statement from COVAX partners (23 September 2021). Available at: https://www.unicef....
- CEPI. COVAX: CEPI's response to COVID-19. Available at: https://cepi.net/covax/0. Last accessed October 2021.
- UNICEF. Global leaders commit further support for global equitable access to COVID-19 vaccines and COVAX A joint statement from COVAX partners (23 September 2021). Available at: https://www.unicef....
- CEPI. COVAX: CEPI's response to COVID-19. Available at: https://cepi.net/covax/0. Last accessed October 2021.
- CEPI. COVAX Global Supply Forecast. Available at: https://www.gavi.org/sites/default/files/covid/covax/COVAX-Supply-Forecast.pdf. Last accessed October 2021.
- WHO. COVAX. Available at: https://www.who.int/initiatives/act-accelerator/covax. Last accessed October 2021.
Further Reading
Comvax Vaccine Description
COMVAX® [Haemophilus b Conjugate (Meningococcal Protein Conjugate) and Hepatitis B (Recombinant) Vaccine] is a sterile bivalent vaccine made of the antigenic components used in producing PedvaxHIB® [Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate)] and RECOMBIVAX HB® [Hepatitis B …
Comvax Vaccine - Clinical Pharmacology
- Haemophilus influenzae type b Disease
Prior to the introduction of Haemophilus b conjugate vaccines, Haemophilus influenzae type b (Hib) was the most frequent cause of bacterial meningitis and a leading cause of serious, systemic bacterial disease in young children worldwide.{1-4} Hib disease occurred primarily in c… - Prevention of Hib Disease with Vaccine
An important virulence factor of the Hib bacterium is its polysaccharide capsule (PRP). Antibody to PRP (anti-PRP) has been shown to correlate with protection against Hib disease.{3,21} While the anti-PRP level associated with protection using conjugated vaccines has not yet been deter…
Indications and Usage For Comvax Vaccine
- COMVAX is indicated for vaccination against invasive disease caused by Haemophilus influenzaetype b and against infection caused by all known subtypes of hepatitis B virus in infants 6 weeks to 15 months of age born of HBsAg negative mothers. Infants born to HBsAg positive mothers should receive Hepatitis B Immune Globulin and Hepatitis B Vaccine (...
Contraindications
- Hypersensitivity to yeast or any component of the vaccine. The decision to administer or delay vaccination because of current or recent febrile illness depends on the severity of symptoms and on the etiology of the disease. The ACIP has recommended that immunization should be delayed during the course of an acute febrile illness.{63} All vaccines can be administered to persons wit…
Warnings
- Patients who develop symptoms suggestive of hypersensitivity after an injection should not receive further injections of the vaccine (see CONTRAINDICATIONS).
Precautions
- General
General care is to be taken by the health-care provider for the safe and effective use of this product. As for any vaccine, adequate treatment provisions, including epinephrine, should be available for immediate use should an anaphylactic or anaphylactoid reaction occur. Use cautio… - Instructions to Health-care Provider
The health-care provider should determine the current health status and previous vaccination history of the vaccinee. The health-care provider should question the patient, parent or guardian about reactions to a previous dose of COMVAX, PedvaxHIB or other Haemophilus b conjugate v…
Adverse Reactions
- In clinical trials involving the administration of 7918 doses of COMVAX to 3561 healthy infants 6 weeks to 15 months of age, COMVAX was generally well tolerated. In these studies, infants received COMVAX with licensed pediatric vaccines (n=1745) or investigational vaccines (n=1816). Serious adverse experience data were available for all 3561 infants and non-serious adverse exp…
How Is Comvax Vaccine Supplied
- No. 4898 — COMVAX is supplied as 7.5 mcg PRP polysaccharide conjugated to approximately 125 mcg OMPC and 5 mcg HBsAg in a box of 10 single dose vials. NDC0006-4898-00.
References
- Cochi, S.L., et al. JAMA 253:521-529, 1985.
- Schlech, W.F., III, et al. JAMA 253:1749-1754, 1985.
- Peltola, H., et al. N Engl J Med 310:1561-1566, 1984.
- Cardoz, M., et al. Bull WHO 59:575-584, 1981.
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