what are some signs and symptoms a patient on warfarin should report to thier docotr

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Warfarin side effects: Watch for interactions - Mayo Clinic

11 hours ago  · Rarely, warfarin can cause the death of skin tissue (necrosis). This complication occurs within a few days of starting warfarin treatment. Seek immediate medical care if you notice sores, changes in skin color or temperature, or severe pain on your skin. Talk to your health care provider about these less serious side effects. >> Go To The Portal


Excessive bleeding can occur in any area of the body, and patients taking warfarin should report any falls or accidents, as well as signs or symptoms of bleeding or unusual bruising, to their healthcare provider. Signs of unusual bleeding include bleeding from the gums, blood in the urine, bloody or dark stool, a nosebleed, or vomiting blood.

Excessive bleeding, or hemorrhage, can occur from any area of the body even if the warfarin is having the desired (rather than an excessive) effect, and people on warfarin should report any falls or accidents, as well as signs or symptoms of bleeding or unusual bruising.Jun 16, 2021

Full Answer

What to know before taking warfarin?

A Patient's Guide to Taking Warfarin 1 The formation of a clot in the body is a complex process... 2 Monitoring and Dosing Tips. The goal of warfarin therapy is to decrease the clotting tendency... 3 Difference Between Brand-Name and Generic Medications. 4 Warfarin must be taken exactly as prescribed. 5 Side Effects. The major complications...

What are the symptoms of excessive bleeding from warfarin?

Excessive bleeding can occur in any area of the body, and patients taking warfarin should report any falls or accidents, as well as signs or symptoms of bleeding or unusual bruising, to their healthcare provider. Signs of unusual bleeding include: bleeding from the gums, blood in the urine,

What are the risks of taking warfarin?

The same action of warfarin that prevents blood clotting can result in bleeding. Warfarin treatment requires careful monitoring. Certain foods, medications, diet changes and illnesses can interfere with warfarin and increase your risk of bleeding.

Why does my warfarin dose keep changing?

The extent to which warfarin is working is measured by the International Normalised Ratio (INR), which is a measure of the ability of your blood to prevent clotting. The amount of warfarin that you need to take will depend upon the result of these blood tests, and this is why your dose may change from time to time.

What are some signs and symptoms a patient on warfarin therapy should immediately report to the doctor?

If you experience any of the following symptoms, call your doctor immediately: pain, swelling, or discomfort, bleeding from a cut that does not stop in the usual amount of time, nosebleeds or bleeding from your gums, coughing up or vomiting blood or material that looks like coffee grounds, unusual bleeding or bruising, ...

What are the symptoms of too much warfarin?

You have a severe headache or dizziness. You have heavy bleeding that does not stop. You have severe stomach pain or you vomit blood. Your urine is pink, red, or dark brown.

What should I monitor for warfarin?

Monitoring Warfarin If the dose of warfarin is too high, the patient may be at risk of serious bleeding. It can be monitored by drawing blood from a vein and sending the blood to an accredited laboratory to test, or it can be monitored by testing blood from a fingerstick with an INR test meter outside of a laboratory.

What is the most common complication of warfarin therapy?

Bleeding is the most serious and common complication of warfarin treatment. For any given patient, the potential benefit from prevention of thromboembolic disease needs to be balanced against the potential harm from induced haemorrhagic side effects.

What happens if your warfarin levels are too high?

A value higher than 3.5 increases the risk of bleeding problems. Many things can affect the way warfarin works. Some natural health products and other medicines can make warfarin work too well. That can raise the risk of bleeding.

What are the symptoms of internal bleeding from blood thinners?

Signs of excessive bleeding can include:passing blood in your urine.passing blood when you poo or having black poo.severe bruising.prolonged nosebleeds (lasting longer than 10 minutes)vomiting blood or coughing up blood.sudden severe back pain.difficulty breathing or chest pain.More items...

What are the symptoms of high INR levels?

Signs of bleeding or a high INR are: Gums bleed when you brush your teeth. Coughing up blood. Vomit that looks like coffee grounds. Bruising in unusual areas or for unknown reasons.

What are the symptoms of low INR?

These symptoms may include swelling, redness, tenderness and/or warmth in one leg or one area of one leg and generalized leg pain, difficulty breathing, chest pain, shortness of breath, breathing quickly, dizziness, Page 2 increased heart rate or low blood pressure, partial or total paralysis, inability to speak or ...

Does warfarin affect blood pressure?

Warfarin causes extensive vascular calcification leading to increased systolic blood pressure and pulse pressure in rats, may be associated with increased valvular and coronary calcifications in man, and possibly worsens hypertension in high-risk patients, particularly in those with diabetes mellitus or uncontrolled ...

What are two common indications for warfarin?

The three most common indications for warfarin therapy are; • atrial fibrillation (AF) • venous thromboemolism (VTE), and • prosthetic heart valves. Atrial fibrillation is probably the most common indication for warfarin therapy in our community.

Which symptom is indicative of bleeding in a patient taking warfarin Coumadin )?

Signs of internal bleeding include severe headache or changes in strength in one part of the body, blood in the urine, bloody or dark stool, or vomiting blood. These signs should prompt immediate discussion with your healthcare provider, who may order a PT/INR test and an in-person evaluation.

What are the risks and toxicities associated with warfarin therapy?

Hemorrhage. Bleeding is the primary adverse effect of warfarin and superwarfarin toxicity and is related to the intensity of anticoagulation, length of therapy, the patient's underlying clinical state, and use of other drugs that may affect hemostasis or interfere with warfarin metabolism.

What is a critical INR level?

Normal and Critical Findings INR levels above 4.9 are considered critical values and increase the risk of bleeding.

Is tiredness a side effect of warfarin?

Report any symptoms that seem alarming, get worse, or worry you. Less serious warfarin side effects may include: Tiredness.

What are the symptoms of a low INR?

These symptoms may include swelling, redness, tenderness and/or warmth in one leg or one area of one leg and generalized leg pain, difficulty breathing, chest pain, shortness of breath, breathing quickly, dizziness, Page 2 increased heart rate or low blood pressure, partial or total paralysis, inability to speak or ...

How long can you stay on warfarin?

As a general rule warfarin is prescribed to treat a blood clot for 3 – 6 months. For an irregular heart beat, recurrent blood clots or some heart valve problems, warfarin is prescribed indefinitely. When should you take your warfarin? Warfarin works best if it is taken at the same time each day.

When Is Warfarin prescribed?

You might be given warfarin if you have: 1. A blood clot in or near your heart that could trigger stroke, heart attack or organ damage 2. A blood c...

What Warfarin Side Effects Should You Watch for?

When you take warfarin, your blood won't clot as easily. If you accidentally cut yourself while taking warfarin, you may bleed heavily. However, th...

Warfarin Side Effects That Require Immediate Medical Attention

1. Severe bleeding, including heavier than normal menstrual bleeding 2. Red or brown urine 3. Black or bloody stool 4. Severe headache or stomach p...

Less-Serious Warfarin Side Effects to Tell Your Doctor About

1. Bleeding from the gums after you brush your teeth 2. Bleeding between menstrual periods 3. Diarrhea, vomiting or inability to eat for more than...

What Precautions Can You Take Against Warfarin Side Effects?

To reduce your chance of developing warfarin side effects: 1. Tell your doctor about any other medications or supplements you take. Many medication...

What Drugs and Supplements Can Interact With Warfarin?

Like any other medication, warfarin can interact with foods, other drugs, vitamins or herbal supplements. The interaction might lower the effective...

What Foods and Drinks Might Interact With Warfarin?

Foods and drinks that might interact with warfarin include: 1. Cranberries or cranberry juice 2. Alcohol 3. Foods that are high in vitamin K, such...

What Should You Do If You Forget A Dose?

Never take a double dose of warfarin. Doing so could greatly increase your risk of side effects.If you miss a dose, take it as soon as you remember...

What Is Warfarin Toxicity?

Warfarin toxicity happens when you have too much warfarin in your body. Certain changes to foods and medicines can also increase the effect of warf...

What Increases My Risk For Warfarin Toxicity?

1. You take higher doses of warfarin than is recommended by your healthcare provider. 2. Your risk of warfarin toxicity increases if you do not hav...

What Are The Signs and Symptoms of Warfarin Toxicity?

1. Red spots on your skin that look like a rash 2. Severe headache or dizziness 3. Heavy bleeding after an injury 4. Heavy bleeding during monthly...

How Do I Safely Take Warfarin?

1. Go to all your follow-up appointments. Your healthcare provider will need to monitor you closely while you are taking warfarin. He may need to a...

What Else Should I Do While I Am Taking Warfarin?

Wear medical alert jewelry or carry a card that says you take warfarin. Ask where to get these items.

When Should I Seek Immediate Care?

1. You have a severe headache or dizziness. 2. You have heavy bleeding that does not stop. 3. You have severe stomach pain or you vomit blood. 4. Y...

When Should I Contact My Healthcare Provider?

1. You have fever and chills. 2. Your gums bleed when you brush your teeth. 3. You have frequent nosebleeds. 4. You bruise easily. 5. You have red...

How to reduce bleeding while taking warfarin?

Some simple changes to decrease the risk of bleeding while taking warfarin include the following: Use a soft-bristle toothbrush. Floss with waxed floss rather than unwaxed floss. Shave with an electric razor rather than a blade. Take care when using sharp objects, such as knives and scissors.

How does warfarin affect blood clotting?

The goal of warfarin therapy is to decrease the clotting tendency of blood, not to prevent clotting completely. Therefore, the effect of warfarin must be monitored carefully with blood testing. On the basis of the results of the blood test, your daily dose of warfarin will be adjusted to keep your clotting time within a target range. The blood test used to measure the time it takes for blood to clot is referred to as a prothrombin time test, or protime (PT). The PT is reported as the International Normalized Ratio (INR).

What is the INR of a PT?

The INR is a standardized way of expressing the PT value. The INR ensures that PT results obtained by different laboratories can be compared. It is important to monitor the INR (at least once a month and sometimes as often as twice weekly) to make sure that the level of warfarin remains in the effective range. If the INR is too low, blood clots will not be prevented, but if the INR is too high, there is an increased risk of bleeding. This is why those who take warfarin must have their blood tested so frequently.

Why is warfarin called an anticoagulant?

Because warfarin interferes with the formation of blood clots, it is called an anticoagulant (PDF). Many people refer to anticoagulants as *blood thinners; however, warfarin does not thin the blood but instead causes the blood to take longer to form a clot.

What to wear for warfarin?

Wear Medical Identification. Those who require long-term warfarin should wear a medical alert bracelet, necklace, or similar alert tag at all times. If an accident occurs and the person is too ill to communicate, a medical alert tag will help responders provide appropriate care.

What are the signs of bleeding?

If you experience the following signs of bleeding, you should call 911 or your healthcare provider immediately: Severe headache, confusion, weakness or numbness. Coughing up large amounts of bright red blood. Vomiting blood.

Does warfarin help with blood clots?

Warfarin decreases the body’s ability to form blood clots by blocking the formation of vitamin K–dependent clotting factors. Vitamin K is needed to make clotting factors and prevent bleeding. Therefore, by giving a medication that blocks the clotting factors, your body can stop harmful clots from forming and prevent clots from getting larger.

How Does Warfarin Work?

Warfarin decreases the body’s ability to form blood clots by blocking the formation of vitamin K–dependent clotting factors. Vitamin K is needed to make clotting factors and prevent bleeding. Therefore, by giving a medication that blocks the clotting factors, your body can stop harmful clots from forming and prevent clots from getting larger.

How does warfarin affect blood clotting?

The goal of warfarin therapy is to decrease the clotting tendency of blood, not to prevent clotting completely. Therefore, the effect of warfarin must be monitored carefully with blood testing. On the basis of the results of the blood test, your daily dose of warfarin will be adjusted to keep your clotting time within a target range. The blood test used to measure the time it takes for blood to clot is referred to as a prothrombin time test, or protime (PT). The PT is reported as the International Normalized Ratio (INR).

How does alcohol affect warfarin?

Alcohol - Alcohol intake can affect how the body metabolizes warfarin. Patients undergoing warfarin therapy should avoid drinking alcohol on a daily basis. Alcohol should be limited to no more than 1 to 2 servings of alcohol occasionally. This means an average of one to two drinks per day for men and one drink per day for women. (A drink is one 12 oz. beer, 4 oz. of wine, 1/5 oz. of 80-proof spirits, or 1 oz. of 100-proof spirits). The antiplatelet effect of alcohol increases the risk of major bleeding, even if the INR remains within the target range.

What is the purpose of warfarin?

Warfarin (brand names Coumadin and Jantoven) is a prescription medication used to prevent harmful blood clots from forming or growing larger. Beneficial blood clots prevent or stop bleeding, but harmful blood clots can cause a heart attack, stroke, deep vein thrombosis or pulmonary embolism. Because warfarin interferes with the formation of blood clots, it is called an anticoagulant (PDF). Many people refer to anticoagulants as *blood thinners; however, warfarin does not thin the blood but instead causes the blood to take longer to form a clot.

Does warfarin cause bruising?

The major complications associated with warfarin are clotting due to underdosing or bleeding due to excessive anticoagulation. The most serious bleeding is gastrointestinal or intracerebral. Excessive bleeding can occur in any area of the body, and patients taking warfarin should report any falls or accidents, as well as signs or symptoms of bleeding or unusual bruising, to their healthcare provider.

Do you have to stop taking warfarin?

It is important to tell all your healthcare providers that you are taking warfarin. If you are having surgery, dental work, or other medical procedures, you may need to stop taking warfarin .

What else should I do while I am taking warfarin?

Wear medical alert jewelry or carry a card that says you take warfarin. Ask where to get these items.

How do I safely take warfarin?

Go to all your follow-up appointments. Your healthcare provider will need to monitor you closely while you are taking warfarin. He may need to adjust your dose based on your INR results.

What is warfarin toxicity?

Warfarin toxicity happens when you have too much warfarin in your body. Certain changes to foods and medicines can also increase the effect of warfarin. Warfarin is a medicine that is used to prevent or treat the formation of blot clots. It works by making your blood clot more slowly. Warfarin toxicity can cause bleeding that can become life-threatening.

How to keep INR stable?

Talk to your healthcare provider before you start or stop any medicines. Eat the same amount of vitamin K daily to help keep your INR stable. Vitamin K is found in green leafy vegetables, broccoli, grapes, and other foods. Ask your healthcare provider for more information about vitamin K. Avoid alcohol.

What is the INR of blood?

The INR, or International Normalized Ratio, is a measure of how long it takes your blood to clot. Your risk of bleeding increase over time when your INR is too high. A sudden decrease of vitamin K in your diet can increase your risk of bleeding. Vitamin K changes how your blood clots.

Can you take warfarin if you miss a dose?

Take this medicine exactly as directed. Contact your healthcare provider if you miss a dose or you have any questions about how to take warfarin.

Can you take warfarin if you don't have an INR?

You take higher doses of warfarin than is recommended by your healthcare provider. Your risk of warfarin toxicity increases if you do not have your INR checked as recommended. Your healthcare provider adjusts your dose based on your INR.

How to tell if you are taking warfarin?

You are taking warfarin to help protect you from having a blood clot or prevent you from getting another one. Call your health-care provider if you have: 1 Painful and constant swelling or redness in your feet, lower legs, or arms 2 Bad headache 3 Blurred vision 4 Dizziness 5 Trouble breathing 6 Chest pain 7 Feelings of severe weakness 8 Numbness or tingling of hands, feet, or face 9 Not being able to move 10 Sudden confusion

What are the side effects of warfarin?

What are side effects of warfarin? Side effects from warfarin are not common, but can happen. The most common side effect is bleeding. To lower your chance of bleeding, your INR should be in the range set for you. If you have any of the side effects listed below, tell your health-care provider right away. You may need to change your dose.

How to tell if INR is high?

Signs of bleeding or a high INR: Bleeding from cuts that do not stop. Nosebleeds that do not stop. Gums bleed when you brush your teeth. Coughing up blood. Vomit (throw-up) that looks like coffee grounds. Bruising for unknown reasons. Heavy periods or unexpected bleeding from the vagina.

What are signs of a blood clot?

You are taking warfarin to help protect you from having a blood clot or prevent you from getting another one. Call your health-care provider if you have:

How Does Warfarin Work?

Warfarin decreases the body’s ability to form blood clots by blocking the formation of vitamin K–dependent clotting factors. Vitamin K is needed to make clotting factors and prevent bleeding. Therefore, by giving a medication that blocks the clotting factors, your body can stop harmful clots from forming and prevent clots from getting larger.

What is the purpose of Warfarin?

Warfarin (brand names Coumadin and Jantoven) is a prescription medication used to prevent harmful blood clots from forming or growing larger. Beneficial blood clots prevent or stop bleeding, but harmful blood clots can cause a stroke, heart attack, deep vein thrombosis, or pulmonary embolism.

What is the purpose of taking Coumadin?

Warfarin (brand names Coumadin and Jantoven) is a prescription medication used to prevent harmful blood clots from forming or growing larger. Beneficial blood clots prevent or stop bleeding, but harmful blood clots can cause a stroke, heart attack, deep vein thrombosis, or pulmonary embolism.

Why is warfarin called an anticoagulant?

Because warfarin interferes with the formation of blood clots, it is called an anticoagulant. Many people refer to anticoagulants as “blood thinners”; however, warfarin does not thin the blood but instead causes the blood to take longer to form a clot.

What is the PT in blood work?

The blood test used to measure the time it takes for blood to clot is referred to as a prothrombin time test, or protime (PT). The PT is reported as the International Normalized Ratio (INR). The INR is a standardized way of expressing the PT value.

Does warfarin help with blood clotting?

The goal of warfarin therapy is to decrease the clotting tendency of blood, not to prevent clotting completely.Therefore, the effect of warfarin must be monitored carefully with blood testing. On the basis of the results of the blood test, your daily dose of warfarin will be adjusted to keep your clotting time within a target range.

Can you increase or decrease Warfarin?

Warfarin must be taken exactly as prescribed. Never increase or decrease your dose unless instructed to do so by your healthcare provider. If a dose is missed or forgotten, call your healthcare provider for advice.

What happens if you take too much warfarin?

If you take too much: Taking too much warfarin can lead to life-threatening bleeding. If you think you've taken too much of this drug, act right away. Call your doctor or local poison control center or go to the nearest emergency room.

What does it mean when your PT is too high?

When your PT or INR is too high, you have an increased risk of bleeding.

Does warfarin cause calcification?

Warfarin causes extensive vascular calcification leading to increased systolic blood pressure and pulse pressure in rats, may be associated with increased valvular and coronary calcifications in man, and possibly worsens hypertension in high-risk patients, particularly in those with diabetes mellitus or uncontrolled

How does warfarin work?

Warfarin is an anticoagulant, which means that it increases the time it takes for your blood to clot. It works by reducing the effects of vitamin K , which is a vitamin your body uses in the process of blood-clotting. Warfarin is used to prevent unwanted clots from forming if you have a condition that puts you at risk of this happening, ...

What is the yellow booklet for warfarin?

You will be given a yellow anticoagulant treatment booklet; read this carefully as it gives you information about when you should contact a doctor for advice. Carry it with you at all times in case of an emergency and a doctor needing to know that you are on warfarin, and at what dose.

Why is warfarin used for a clot?

Warfarin is used to prevent unwanted clots from forming if you have a condition that puts you at risk of this happening, such as atrial fibrillation. It is also used to prevent any clots that may have already formed in the blood vessels of your legs, lungs or heart from becoming larger and causing problems.

How does changing diet affect INR?

A major change in diet may mean that you need closer monitoring and may need a change in warfarin dose .

How many strengths of Warfarin are there?

Warfarin tablets are available in different strengths. Your dose may be made up of more than one strength of tablet. Each strength of tablet is a different colour to help you tell the difference between them; 0.5 mg tablets are white, 1 mg tablets are brown, 3 mg tablets are blue and 5 mg tablets are pink. If you have been prescribed the oral ...

What is yellow anticoagulant?

It will be prescribed if you have an unwanted clot in your blood, or if you are at risk of having an unwanted clot. You may be given a yellow anticoagulant treatment booklet; read this carefully and carry it with you at all times. You will need to have regular blood tests to measure how quickly your blood clots.

How long does it take to stop taking warfarin?

Continue to take warfarin tablets regularly until your doctor tells you to stop. A course of treatment typically lasts from six weeks to three months, although some people may be advised to continue taking warfarin for longer than this.

WHAT SHOULD BE EATEN?

There is no specific diet which needs to be followed if you are on WARFARIN [COUMADIN] but there are some foods which can make WARFARIN less effective.

Foods that are rich in Vitamin K include –

Fruits such as watermelon, pineapple, bananas, peaches, apple and strawberries.

Why do elderly people underuse anticoagulants?

There is a general tendency among physicians to underuse anticoagulants in the elderly, probably both because of underestimation of thromboembolic risk and overestimation of bleeding risk . Assessing the benefit-risk ratio of anticoagulation is one of the most challenging issues in the individual elderly patient.

Should I go to the ER if I'm on blood thinners?

An elderly person on a blood thinner who falls, even if they claim “I’m fine,” should be taken to the ER just to make sure there are no signs of internal bleeding or a small fracture somewhere.

Can a person on Coumadin have internal bleeding?

An elderly person on Coumadin who falls is at risk for internal bleeding – and this risk is substantial. Even if they don’t strike their head, they can still end up with a brain bleed (simply from the jarring motion of the fall).

Can coumadin be revoked?

But if the patient sees a doctor in the name of making sure everything is alright, they risk getting the coumadin prescription revoked.

Can you anticoagulate an elderly person with AF?

The decision to anticoagulate an elderly person with AF at high risk for stroke is a common problem faced by physicians. ( NYU Langone Online Journal of Medicine)

Can you prescribe Coumadin for atrial fibrillation?

Studies have shown that physicians are hesitant to prescribe antithrombotic therapy [coumad in] in elderly patients with atrial fibrillation who are perceived to have an increased fall risk, to prevent inducing an intracranial hemorrhage. (NYU Langone Online Journal of Medicine)

Can an elderly person take Coumadin?

An elderly person on Coumadin takes a bad fall, but if you take them to the doctor this will result in a prescription cancellation for the blood thinner. Your elderly parent is on coumadin (Warfarin) for stroke prevention. But they’re also at risk for falling. Let’s take my very elderly father as an example.

Overview

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Warfarin (brand names Coumadin and Jantoven) is a prescription medication used to prevent harmful blood clots from forming or growing larger. Beneficial blood clots prevent or stop bleeding, but harmful blood clots can cause a heart attack, stroke, deep vein thrombosis or pulmonary embolism. Because warfarin interferes with the formation of blood c...
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Mechanism

  • The formation of a clot in the body is a complex process that involves multiple substances called clotting factors. Warfarin decreases the bodys ability to form blood clots by blocking the formation of vitamin Kdependent clotting factors. Vitamin K is needed to make clotting factors and prevent bleeding. Therefore, by giving a medication that blocks the clotting factors, your body can stop harmful clots from forming and prevent clots from getting larger.
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Treatment

  • The goal of warfarin therapy is to decrease the clotting tendency of blood, not to prevent clotting completely. Therefore, the effect of warfarin must be monitored carefully with blood testing. On the basis of the results of the blood test, your daily dose of warfarin will be adjusted to keep your clotting time within a target range. The blood test used to measure the time it takes for blood to clot is referred to as a prothrombin time test, or protime (PT). …
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Purpose

  • The INR is a standardized way of expressing the PT value. The INR ensures that PT results obtained by different laboratories can be compared. It is important to monitor the INR (at least once a month and sometimes as often as twice weekly) to make sure that the level of warfarin remains in the effective range. If the INR is too low, blood clots will not be prevented, but if the INR is too high, there is an increased risk of bleeding. This is why those wh…
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Administration

  • Unlike most medications that are administered as a fixed dose, warfarin dosing is adjusted according to the INR blood test results; therefore, the dose usually changes over time. Coumadin/ warfarin pills come in different colors, and each color corresponds to a different dose (see graphic below).
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Risks

  • The major complications associated with warfarin are clotting due to underdosing or bleeding due to excessive anticoagulation. The most serious bleeding is gastrointestinal or intracerebral. Excessive bleeding can occur in any area of the body, and patients taking warfarin should report any falls or accidents, as well as signs or symptoms of bleeding or unusual bruising, to their healthcare provider.
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Diagnosis

  • If you experience the following signs of bleeding, you should call 9-1-1 or your healthcare provider immediately:
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Significance

  • Changes in daily living can affect the INR. It is important to know common dos and donts for warfarin therapy.
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Contraindications

  • Warfarin is not recommended during pregnancy. A woman who becomes pregnant or plans to become pregnant while undergoing warfarin therapy should notify her healthcare provider immediately.
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Preparation

  • It is important to tell all your healthcare providers that you are taking warfarin. If you are having surgery, dental work, or other medical procedures, you may need to stop taking warfarin.
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Interactions

  • Patients who take warfarin should consult with their healthcare provider before taking any new medication, including over-the-counter (nonprescription) drugs, herbal medicines, vitamins or any other products. Many medications can alter the effectiveness of warfarin, resulting in an INR that is either too high or too low. Some of the most common over-the-counter pain relievers, such as: ibuprofen (brand name Advil) and naproxen (brand n…
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