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Does Sophora flavescens (Ku shen) prevent cancer?

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What is Sophora flavescens used for?

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What is the effect of sophora flavescens on the liver?

Sophora flavescens or Ku Shen, which in Chinese means “bitter root,” is an herb used in Traditional medicine to treat a wide variety of symptoms, with purported effects on the liver, intestinal tract, and skin. Lab and animal studies have shown that some compounds can kill cancer cells and help fight certain viruses.

What is the scientific name of Sophora flavescens?

Scientific Name. Sophora flavescens. Clinical Summary. Sophora flavescens is a deciduous shrub related to peas. The root known as “Ku Shen” which means “bitter root” in Chinese, has been used in Traditional Medicine for two thousand years to treat a variety of conditions including diarrhea, jaundice, and skin rashes, and to kill parasites (1). ...

What is the main alkaloid in S. flavescens?

Most reported antineoplastic effects of S.flavescens are due to the proapoptotic activity of matrine, the main alkaloid constituent. In human hepatocellular carcinoma cells, matrine inhibits matrix metalloproteinase-9 (MMP-9) by downregulating the NF-kappa B pathway (18).

Is Sophora flavescens effective against coxsackie B?

Limited evidence suggests that a compound from Sophora flavescens may be useful for hepatitis B and coxsackie B viruses , but more data are necessary to support this use.

Does Sophora flavescens increase the activity of antibiotics against oral bacteria?

You are taking ampicillin/gentamicin: In the lab, one of the compounds in Sophora flavescens increased the activity of these antibiotics against oral bacteria. Clinical relevance has yet to be determined. You have a hormone-sensitive cancer: Sophora flavescens has estrogenic effects and may stimulate the proliferation of hormone-sensitive cancer ...

Is Sophora flavescens safe for humans?

This will help them manage your care and keep you safe. Sophora flavescens has shown anticancer effects in lab studies, but has not been studied for cancer prevention or treatment in humans. Sophora flavescens or Ku Shen, which in Chinese means “bitter root,” is an herb used in Traditional medicine to treat a wide variety of symptoms, ...

Does Sophora flavescens kill cancer cells?

Lab and animal studies have shown that some compounds can kill cancer cells and help fight certain viruses. However, human data are lacking. Sophora flavescens may act like an estrogen in the body. Patients with hormone-sensitive cancer should avoid this product. Purported Uses. Cancer treatment.