9 hours ago · You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. >> Go To The Portal
What are some things I need to know or do while I take Cytoxan? 1 Tell all of your health care providers that you take Cytoxan (cyclophosphamide injection). 2 Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight... 3 Very bad and sometimes deadly allergic side effects have rarely happened...
Patients who received an overdose should be closely monitored for the development of toxicities, and hematologic toxicity in particular. Cytoxan (cyclophosphamide) and its metabolites are dialyzable. Therefore, rapid hemodialysis is indicated when treating any suicidal or accidental overdose or intoxication.
Cytoxan 1 DESCRIPTION. Cytoxan (cyclophosphamide) is a synthetic antineoplastic drug chemically related to... 2 INDICATIONS. Cyclophosphamide, although effective alone in susceptible malignancies,... 3 DOSAGE AND ADMINISTRATION. During or immediately after the administration, adequate amounts...
Use birth control that you can trust to prevent pregnancy while taking Cytoxan (cyclophosphamide injection) and for up to 12 months after Cytoxan (cyclophosphamide injection). If you get pregnant while taking Cytoxan (cyclophosphamide injection) or within 12 months after your last dose, call your doctor right away.
Uses for Cytoxan. Cyclophosphamide is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cyclophosphamide is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin).
Gout, history of or. Kidney stones, history of—Cyclophosphamide may increase levels of uric acid in the body, which can cause gout or kidney stones. Infection—May decrease body's ability to fight infection.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abametapir. Adenovirus Vaccine.
Taking too much may increase the chance of side effects, while taking too little may not improve your condition. Cyclophosphamide is sometimes given together with certain other medicines. If you are using a combination of medicines, make sure that you take each one at the proper time and do not mix them.
Cytoxan side effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
Medically reviewed by Drugs.com. Last updated on Nov 20, 2020. The Cytoxan brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Since the growth of normal body cells may also be affected by cyclophosphamide, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.
Cyclophosphamide is the generic name for the trade name drug Cytoxan or Neosar. In some cases, health care professionals may use the trade name Cytoxan or Neosar when referring to the generic drug name cyclophosphamide.
Before starting cyclophosphamide treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.) Do not take aspirin or products containing aspirin unless your doctor specifically permits this.
Tell your doctor if you have unlikely but serious side effects of Cytoxan including: pink/bloody urine, unusual decrease in the amount of urine, mouth sores, unusual tiredness or weakness,
When used as the only oncolytic drug therapy, the initial course of cyclophosphamide for patients with no hematologic deficiency usually consists of 40 mg per kg to 50 mg per kg given intravenously in divided doses over a period of 2 to 5 days.
During transport or storage of cyclophosphamide vials, temperature influences can lead to melting of the active ingredient, cyclophosphamide [see DOSAGE AND ADMINISTRATION ]. Cyclophosphamide Tablets, USP are white tablets with blue flecks containing 25 mg and 50 mg cyclophosphamide, respectively.
Cytoxan (cyclophosphamide) is a synthetic antineoplastic drug chemically related to the nitrogen mustards. The chemical name for cyclophosphamide is 2- [bis (2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate, and has the following structural formula:
Cytoxan (cyclophosphamide) is a cancer ( chemotherapy) medication used to treat several types of cancer. Cytoxan is also used to treat certain cases of nephrotic syndrome (kidney disease) in children.
Cyclophosphamide is biotransformed principally in the liver to active alkylating metabolites by a mixed function microsomal oxidase system. These metabolites interfere with the growth of susceptible rapidly proliferating malignant cells.
Cyclophosphamide can cause fetal harm when administered to a pregnant woman based on its mechanism of action and published reports of effects in pregnant patients or animals. Exposure to cyclophosphamide during pregnancy may cause fetal malformations, miscarriage, fetal growth retardation, and toxic effects in the newborn. Cyclophosphamide is teratogenic and embryo-fetal toxic in mice, rats, rabbits and monkeys. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, apprise the patient of the potential hazard to a fetus.
Since cyclophosphamide remains in your body for several days after it is taken , some of the drug may be present in urine, stool, sweat, or vomit. Once you have started to take cyclophosphamide, it is important to know the following instructions every day for as long as your treatment lasts. This is to keep yourself, loved ones, and the environment as safe as possible.
Bone marrow suppression is a decrease in the number of white blood cells, red blood cells and platelets that can be severe with cyclophosphamide. Speak to your care provider to know when you need to have laboratory tests done to monitor your blood cell counts. You also may need to take a break or “hold” your medication for medical or dental procedures. Talk to your care provider or dentist before any scheduled procedures. Tell your doctor if you develop a fever or abnormal bleeding.
Women should not become pregnant and men should not get a partner pregnant while taking cyclophosphamide. Men and women of childbearing age and potential should use effective contraception during therapy and for a minimum of 4 months (men) to 12 months (women) after the last dose of cyclophosphamide.
Decrease in the number of circulating white blood cells (leukopenia) which may increase your risk of infection. Decrease in platelet count (thrombocytopenia) whichmay increase risk your of bleeding. Decrease in red-blood cell count. Infertility in males and in females.
Decreases blood concentrations of cyclophosphamide. Thiazides may increase the toxic effects of cyclophosphamide, particularly decreased white blood cell count.
You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
If you need to store Cytoxan (cyclophosphamide injection) at home, talk with your doctor, nurse, or pharmacist about how to store it. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs.
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Cytoxan (cyclophosphamide injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking ...
This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. In both men and women, this may go back to normal but sometimes it may not. Talk with your doctor. Periods may stop in women treated with Cytoxan (cyclophosphamide injection).
Very bad and sometimes deadly liver problems have happened with Cytoxan (cyclophosphamide injection). Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
This may not go back to normal. Women treated with Cytoxan (cyclophosphamide injection) may go through menopause at a younger age than normal. Talk with your doctor. This medicine may cause harm to the unborn baby or loss of the unborn baby if you take it while you are pregnant.