beta-1a for relapsing-remitting ms. the patient calls the clinic to report headache

by Lew Mosciski 7 min read

Evidence of interferon beta-1a dose response in relapsing …

25 hours ago Interferon beta-1a represents one of the first-line therapies for relapsing-remitting multiple sclerosis due to its accessibility and efficacy. Case presentation: A 36-year-old woman who was previously diagnosed with relapsing-remitting multiple sclerosis had received weekly intramuscular injections with beta-interferon-1a (Avonex 30 mcg). >> Go To The Portal


What is relapse-remitting multiple sclerosis (MS)?

Relapsing-remitting MS is the most common initial presentation, which is characterized by recurrent, clearly defined episodes of symptoms with periods of remission with relapse occurring approximately twice every 3 years.

How are the symptoms of multiple sclerosis (MS) managed?

Some symptoms may be managed with symptom-specific drugs. A patient has been diagnosed with multiple sclerosis (MS) for 10 years and has a history of 3 periods of neurologic dysfunction lasting several weeks separated by long periods of full recovery.

What are the side effects of Copaxone for relapsing-remitting multiple sclerosis (MS)?

A patient has received an initial dose of glatiramer acetate [Copaxone] for relapsing-remitting multiple sclerosis. The nurse notes that the patient appears flushed and anxious and has urticaria. The patient reports palpitations, chest pain, and a feeling of laryngeal constriction.

What are the side effects of Avonex for relapsing-remitting MS?

A patient is being treated with interferon beta-1a [Avonex] for relapsing-remitting MS. The patient calls the clinic to report headache, fever, chills, and muscle aches after administering a dose. What will the nurse recommend?

How does peginterferon beta-1a work for MS?

Peginterferon beta-1a injection is in a class of medications called immunomodulators. It works by decreasing inflammation and preventing nerve damage that may cause symptoms of multiple sclerosis.

Is interferon beta-1a used to treat MS?

Interferon beta-1a injection is used to treat the relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.

Which medication is most appropriate for a patient newly diagnosed with relapsing remitting multiple sclerosis MS )?

Starting with high efficacy therapy — An approach favored by some experts is to start most patient with RRMS using one of the high efficacy DMTs, such as natalizumab, ocrelizumab, and ofatumumab.

What medication is used for relapsing remitting MS?

Ocrelizumab (Ocrevus). This humanized monoclonal antibody medication is the only DMT approved by the FDA to treat both the relapse-remitting and primary-progressive forms of MS .

What is beta interferon used for?

Interferon beta-1b injection is used to reduce episodes of symptoms in patients with relapsing-remitting (course of disease where symptoms flare up from time to time) of multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness, numbness, loss of muscle ...

How does beta interferon help MS?

How do beta interferons work? Your body makes its own interferons (a protein) to dampen down inflammation. These drugs are manmade versions. They can reduce (and might prevent) the inflammation that damages nerves in MS.

What is the first line treatment for acute episodes of relapsing-remitting MS?

Interferon beta-1b therapy The first medication approved by the FDA for MS, in 1993, was interferon beta-1b (Betaseron, Extavia). It is indicated for the treatment of relapsing forms of MS to reduce the frequency of clinical exacerbations.

What are 3 drugs to treat multiple sclerosis?

Lemtrada® (alemtuzumab)Novantrone® (mitoxantrone)Ocrevus® (ocrelizumab)Tysabri® (natalizumab)

What drug class is first line treatment for multiple sclerosis?

There are currently five DMDs used as first line treatments for relapsing-remitting multiple sclerosis. Beta interferon 1a (available under the trade name Avonex®) – given by injection into a muscle (intramuscular) once a week using a pre-filled syringe.

What is relapsing-remitting MS?

Different types of MS affect people in different ways. One type is called relapsing-remitting MS. With this type, you have flare-ups of the disease, or relapses. Between these flare-ups, you have periods of recovery, or remissions. Most people diagnosed with MS start off with the relapsing-remitting type.

What does relapsing-remitting mean?

Relapsing-remitting MS is defined as MS in which patients have relapses of MS and periods of stability in between relapses. Relapses are episodes of new or worsening symptoms not caused by fever or infection and that last more than 48 hours.

Can Covid cause MS?

Indeed, some studies show that viral respiratory tract infections may be linked to most of the exacerbations of MS (Marrodan et al., 2019). If we focus on the coronavirus (CoV) family, there is clear evidence of its neurotropic character.

What does MS mean in nursing?

A patient has been newly diagnose d with multiple sclerosis (MS), and the nurse provides teaching about the medications for the disease. Which statement by the patient indicates a need for further teaching?

What is the difference between progressive and primary MS?

Primary progressive MS occurs when symptoms grow progressively more intense from the onset. Progressive-relapsing MS is similar to primary progressive MS, but with acute exacerbations imposed on the steadily worsening symptoms.

Why should the provider be notified of depression?

The provider should be notified so that the patient may be monitored and a reduction of dose may be required. Reassuring the patient is not correct because the symptoms may worsen. Patients experiencing depression should be referred to a psychiatrist for treatment.

Does drug therapy help with axons?

Drug therapy can reduce the frequency and severity of relapses , maintain quality of life, and prevent permanent damage to axons, but it does not produce permanent remission. Patients may need to take additional drugs during times of relapse and will need to take medications indefinitely.

Can a nurse tell a patient that her fetus is safe?

The nurse cannot assure her that her fetus is safe and should not counsel abortion. A patient is about to begin therapy with fingolimod [Gilenya] to treat multiple sclerosis. The nurse learns that the patient has not had chickenpox or the varicella zoster virus (VZV) vaccine.